- BIOHEAL / CP-SERUM / EMU-OIL / EXFOL
CREAM / EXFOL SERUM / GENTLE CLEAN / GLYCOLIC ACID / SALICYLIC ACID / PROTECT &
RESTORE / TRI-REDUCTION
-
-
The best in the world at the best
price!
-
-
BioHeal 4oz US$ 29.95
CpSerum 4oz US$ 33.95
CpSerum+Exfol Serum US$ 51.95
CpSerum Nail Renewal 0.5 oz US$ 24.95
Emu Oil S 2 oz US$ 29.95
Exfol Cream 2% salicylic acid 4oz US$21.95
Exfol Serum 2% salicylic acid 4oz US$24.95
Gentle Clean 8 oz US$ 14.95
Herbal Hydrating Spray 8 fl. oz US$ 13.95, 6 items US$ 81
Herbal Wash 8 fl. oz US$ 17.45, 6 items US$ 94.23
Hydro-Lac Lotion 240ml, 8 fl. oz US$ 22.50, 6 items US$ 129.6
Glycolic-8 4 oz US$ 39.95
Iamin Idrating gel 85g 3 oz tube US$ 29.95, 6 x 3
oz tubes US$ 86.95
Protect & Restore Skin Renewal Cream, Protect & Restore Skin
Renewal Cream with High Retinol and oil of lavander, Protect & Restore Day Cover 4oz
$33.95
Protect & Restore Skin Renewal Cream + Glycolic-8 US$ 51.95
Protect & Restore Suntanning Lotion 8 oz US$ 29.95
TriReduction Basic, TriReduction with retinol 4oz US$ 39.95
TriReduction Glycolic Exfoliator 14% 4oz US$ 24.95
Skin Biology's
new and patented copper peptide technology is Dr. Pickart's most
effective copper peptide system to date. These breakdown-resistant, improved copper
peptides give a longer-acting and stronger skin regeneration and also can be used with
hydroxy acids and Retin-A ® (marchio registrato). The single peptides
(tripeptides or pentapeptides) used in many products are fragile,
short-acting, and cannot be used with hydroxy acids. Extensive safety testing has proven
Skin Biology's copper peptides to be nonallergenic and none irritating. Skin Biology's
copper peptides have neither the allergenic sensitization problems of the bacterial
produced copper peptides nor the biological inactivity ("colorless-copper") of
copper complexes used by some irresponsible cosmetic companies.
Copper-peptides are used clinically
for wound healing, increased skin healing after laser resurfacing and chemical peels, and
for improving the success of hair transplantation. They help stimulate the skin's
regenerative processes which repair the skin's protective outer barrier, increase new
capillary formation (angiogenesis), increase the production of collagen and elastin which
improve skin elasticity and firmness, and the increase the water-holding proteoglycans and
glycosaminoglycans (GAGs) which hold moisture in the skin and are the only
"true" moisturization of skin. They also activate the skin's system (called
metalloproteinases) that removes damaged proteins such as scars and sun damage marks.
Copper-peptides
also improve the skin's anti-oxidant defenses by activating superoxide dismutase (SOD), a
protein which de-toxifies free radicals and that is the body's primary anti-oxidant
defense. Normally SOD lacks enough copper to be active and copper-peptides, by supplying
nutritional copper to SOD, increase the activity of SOD.
When creams
containing copper-peptides are applied to the skin, only very small amounts of the
copper-peptides penetrate into the skin. Copper-peptides have passed numerous safety
tests. Scientific studies of copper-peptides have found that the amount of copper taken
into the body from such copper-peptide creams is insignificant and does not raise total
blood copper levels. However, the microscopic amount of copper-peptide that does
enter the skin's upper layer is sufficient to help stimulate skin regeneration.
Actions of Skin Regenerating
Copper Peptides
Skin Repair |
Increases collagen synthesis producing firmer skin |
|
Increases elastin synthesis producing more elastic skin |
|
Increases synthesis of glycosaminoglycans and
proteoglycans - the skin's water holding proteins |
|
Stimulates new capillary formation for better cellular
nutrition |
|
Attracts macrophages to area of application - these are
the skin repair cells |
|
|
Removal of damaged protein and Scar
Reduction |
Activates metalloproteinases that remove damaged protein |
|
Suppresses production of TGF-beta, the scar producing
factor |
|
|
Anti-inflammatory |
Blocks release of oxidative iron from ferritin |
|
Blocks damaging actions of Interleukin-1 |
|
Activates inert superoxide dismutase |
- Ingredient
|
Biological
Activity |
Effect on skin |
Copper-peptides -
Skin Biology has five US patents on this technology |
Increases activity of skin metalloproteinases
(Copper-peptides are the only known activator of this activity) |
Removes skin proteins damaged by sunlight, oxygen radicals
or
sugar cross links -
Removal allows deposition
of new collagen and elastin |
|
Increases biosynthesis of new collagen and elastin |
Tightens and firms skin |
|
Increases production of proteoglycans and
glycosaminoglycans |
Increases the skin's
internal moisturization |
|
Activates the skin's superoxide dismutase -
Increases the skin's ability to de-toxify oxygen radicals in water areas of skin |
Reduces damage from sun environmental pollutants |
|
Repairs and tightens skin barrier |
Skin become more resistant to irritants and
allergens |
|
Increases size of apocrine glands in skin |
May increase secretion of sexual pheromones for attraction |
|
|
|
Retinol |
Increases wrinkle reduction |
|
|
Increases skin oil |
Eliminates dry skin problems |
|
Decreases breakdown
of undamaged skin proteins |
Excessive breakdown of skin protein occurs after age 45 |
|
|
|
Allantoin |
Improves skin repair |
Helps general skin repair |
|
|
|
Squalane and Octyl Palmitate |
Rebuilds the protective acid mantle |
Increases skin's first line of defense and protection |
|
|
|
Mixed Tocopherols (vitamin E),
mixed tocotrienols,
Coenzyme Q10 |
Inactivate damaging oxygen radicals
in fatty areas of skin |
Reduces damage from sun and environmental pollutants |
|
|
|
Titanium Dioxide - pure - P&R#7 |
Scatters and reflects sunlight and ultraviolet |
A safe sunblocker
Does not penetrate into skin |
- BIOHEAL, improve the health of
"at-risk" skin and help prevent serious damage
- Ingredients : purified water, squalane, octyl palmitate,
glycerol stearate, PEG-100 stearate,
cetyl
alchol,
copper peptides (hydrolyzed soy protein and copper chloride), stearic acid,
allantoin, propylene glycol, camphor, mentol, diazolinydinyl urea, methylparaben,
propylparaben, herbal fragrance, tocopheryl acetate.
- BioHeal contains advanced Copper-Peptides
that help your body to heal damaged skin that is dry, cracked, sore and itches. BioHeal's
Copper-Peptides also have anti-inflammatory properties to help alleviate rashes and
skin irritations and are safer than cortisone and corticosteroids. BioHeal is designed to
help maintain optimal skin health and to help prevent the development of more serious skin
damage and infections in persons with skin that is "At-Risk". Studies at
over 30 leading Universities and Medical Research Institutes by leading dermatologists and
scientists have established the effectiveness on skin repair of Copper-Peptides invented
by Dr. Loren Pickart.
- BioHeal is a product that was developed to help speed skin
repair in conditions that may lead to more serious skin damage, scarring, and infections.
Persons who are at risk for more serious skin damage are those with diabetes, eczema, dry
and cracking skin, skin allergies, psoriasis, immune-compromised status (HIV,
immuno-suppressant therapy after transplants or after from cancer chemotherapy), the
bedridden and persons in wheelchairs, and those with thermal burns and radiation burns.
- BioHeal help enhance the skin's recovery of health after
many types of skin irritations, skin damage and rashes. BioHeal contains our
clinically-proven copper-peptides that form a repair-promoting protective film over the
skin and also acts as a superoxide dismutase that can help de-toxify oxygen radicals that
delay skin repair. BioHeal also rebuilds the skin's natural protective and anti-oxidant
"acid mantle".
- BioHeal is especially useful in
maintaining healthy skin in persons "At-Risk" for skin damage. Persons with:
Diabetes, eczema and dry, cracking skin, psoriasis, immune-compromised status (HIV,
immuno-suppressant therapy), the bedridden and persons in wheelchairs, radiation-burned
skin from cancer therapy, skin allergies such as nickel or poison ivy.
-
The use of BioHeal often rapidly improves skin health in persons at
risk for skin ulcers and bedsores and stops the further development of such sores.
Prevention is much better than healing open skin wounds.
- BioHeal is also
useful to help repair skin after hair removal methods (waxing, shaving, electrolysis) and
rapidly reduces soreness in the skin. It also works well to help heal skin damage caused
by nail polish removers which often produce a dry and cracking skin.
Skin Damaging Conditions and
Effect of Copper-Peptide Creams
Condition
Producing
Skin Damage |
Defect Involved |
Effect of
Copper-Peptide Skin Repair Accelerators |
Diabetes |
Inadequate protein synthesis |
Strong stimulation of repair |
HIV-AIDS condition |
Lack sufficient immune cells for skin repair |
Accelerators concentrate enough immune cells for adequate
repair |
Eczema |
Degraded skin barrier |
Excellent results with creams and non-irritating cleanser |
Contact dermatitis |
Often degraded skin barrier allows passage of irritants |
Rebuilding skin barrier makes skin less sensitive to
irritants |
Dry Skin - Sjorgren's syndrome |
Damaged skin barrier causes excessive water loss |
Excellent results in reliving dry skin. Skin barrier
repaired and the skin's water-holding proteoglycans are increased |
Thermal burns and radiation burns |
"Zone-of-stasis" around injury blocks blood
vessel growth and wound repair |
Accelerators stimulate blood vessel production and
overcome zone-of-stasis barrier |
Post-chemotherapy |
Lack of sufficient immune cells for skin repair |
Accelerators concentrate enough immune cells for adequate
repair |
Skin allergies |
Excessive free radical production produces inflamed
state |
Copper activates superoxide dismutase defenses and reduces
free radicals - skin repair then proceeds to completion |
Psoriasis |
Excessive production of certain types of skin cells leads
to skin barrier damage |
Skin barrier repair often stops itching and flaking -
sometimes removes all problems psoriasis |
- BioHeal is our skin cream specifically designed for repair
"At-Risk" skin. However, our customers also use our Protect & Restore skin
renewal creams for these purposes. The P&R creams have less copper-peptide,and no
camphor or menthol.
- While BioHeal has
the strongest effects on skin repair and has the most pain reduction, the P&R creams
have more aesthetic appeal. P&R often works well. BioHeal has slightly more
copper-peptide and sticks better to damaged skin. BioHeal also contains the non-drug pain
reducers camphor and menthol.
- BioHeal plus Emu Oil
- Within the past year, a number of our customers have told us
of good responses in alleviating or reducing eczema or psoriasis after the combined use of
Emu Oil and BioHeal. The fatty acid composition of human skin oil and emu oil are
very similar. In both oils, mono-unsaturated oleic acid is the most prevalent, then
palmitic acid, followed by the essential fatty acid, linoleic acid. This may be the reason
for the positive actions of emu oil on human skin. (Zemtsov et al
1996)
- A study by Lopez and colleagues (1999) found strong
anti-inflammatory effects of topically applied emu oil after skin was exposed to the a
very strong irritant - croton oil. By 12 hours after applying emu oil, there was
significantly less edema and swelling than controls not treated with the oil.
- Politis and Dmytrowich (1998) found that if emu oil was
applied immediately after a wounding injury, it delayed healing. However, if applied 2
days after injury, it them aided the healing process. So for skin repair, first use
copper-peptides, then start using the emu oil.
- Skin researchers at the University of Texas Medical School
in Houston reported that emu oil at up to 100 % concentration in lotions to be
nonallergenic, non-comedogenic, have low irritation potential, and to be bacteriostatic.
- While scientific studies on emu oil are just beginning, emu
oil has been traditionally used to help alleviate discomfort of arthritis, shingles,
eczema, psoriasis and other inflammatory conditions.
- Why BioHeal Is Better than
Cortisone on Irritated and Damaged Skin
- BioHeal's copper-peptides reduce the need for
the use of corticosteroids for skin dermatitis. Corticosteroids (such as cortisone)
produce damaged and thinned skin (often 50% thinner) by inhibiting the natural skin repair
processes. Use of corticosteroids produces a vicious cycle requiring more corticosteroid
use due to more irritations from the weakened skin. The use can promote diabetic
conditions, thymus involution, immune suppression, the spread of cancers, bone damage, and
cataracts. It is estimated that 5,000 hip replacements yearly in Canada are due to overuse
of corticosteroids.
- During
inflammation, the skin is damaged by immune cells that release toxic oxygen radicals into
the damaged area. The purpose of these oxygen radicals is to kill invading bacteria after
wounding but often the oxygen radicals are released in the absence of any bacteria.
Cortisone and corticosteroids act by killing the immune cells to stop oxygen radical
release but this also kills the immune cells that release the skin repair growth factors
and hence stops skin repair which ultimately leads to a thinned and damaged skin.
- Copper-peptides,
on the other hand, directly detoxify the oxygen radicals. They also transfer copper to
superoxide dismutase (SOD), the skin's primary anti-oxidant protein, which activates the
skin's SOD which further increases the removal of oxygen radicals. Also, the
copper-complexes have been shown to strongly stimulate the skin's repair systems and
improve healing and skin renewal. The above mentioned nickel allergy study demonstrated
both the anti-inflammatory and skin repair properties of copper-peptides. (Zhai, Chang,
Singh, and Maibach, "In vivo nickel contact dermatitis: human model for topical
therapeutics", Contact Dermatitis Vol. 40, pp. 205-208, 1999.)
Comparison: Effect of
Copper Peptide vs Corticosteroids
for Skin Repair and Anti-inflammation
|
Stops Inflammation by |
Effect on Skin Repair and Renewal |
BioHeal -
Copper-Peptide |
1. Detoxifying
oxygen radicals
2. Activating the skin's superoxide dismutase |
Strongly stimulates skin repair and renewal |
Cortisone
& Other Corticosteroids |
1. Killing immune cell macrophages and neutrophils
which secrete
oxygen radicals |
Stops skin repair and renewal by killing macrophages which
secrete skin repair growth factors |
- CP-SERUM, skin rigeneration and glow
- CP Serum is a skin care serum with copper-peptides
that helps skin renewal while enhancing the skin's protective barrier and anti-oxidant
defenses. Customers have told us that the serum enhances facial beauty and gives an
"extra glow". The serum has no lipids and is useful for
persons with high skin oil and for use in very warm regions.
-
The simple ingredients in the serum make it more acceptable for many persons with very
sensitive skin or persons with acne who must limit lipids on their skin.
- CP Serum is compatible when used with
alpha hydroxy acids and Retin-A ® (marchio registrato). CP Serum should not be used at the same time as vitamin C
creams since the copper-peptide inactivates the vitamin C. CP
Serum ingredients : purified water, hydroxyethylcellulose,
copper-peptides (hydrolyzed soy protein chelated to copper chloride), allantoin,
diazolinydinyl urea, methylparaben, propylparaben.
- How to Use - Renewing Your
Skin and Improving Skin Color
- 1.
Apply a small amount of the CP Serum once or twice daily. Start gradually then increase
the amount applied.
-
If your skin is very sensitive or already irritated, start with a very light amount of CP
Serum every other day for a week. This will allow your skin to re-build its natural skin
barrier. Sometimes people with very sensitive skin may have their skin already in a state
of sub-clinical inflammation after the use of many different skin-damaging toners,
astringents, cleansers and moisturizers. Then after the initial week, use more CP
Serum. This approach has worked well for many persons with very sensitive skin who
have a tendency to have skin reactions. Do not use within 12 hours of using a vitamin C
product on your skin.
-
Cautions: In some persons, there may exist previously developed skin allergies to common
cosmetic ingredients. If you notice severe itching or skin reactions after use of either
of the products, discontinue use of the products. The ingredients in CP Serum are
non-irritants, non-allergens, and non-comedogenic and have passed numerous safety tests.
-
- CP-SERUM NAIL RENEWAL
- Ingredients : purified
water, aloe vera gel, squalane, octyl palmitate, glycerol stearate, PEG-100 stearate,
propylene glycol, cetyl alchol, copper peptides (hydrolyzed soy protein and copper
chloride), stearic acid, allantoin, retinol, diazolinydinyl urea, methylparaben,
propylparaben, mixed natural tocotrienols, ubiquinone, ergocalciferol, bronopol.
- During prolonged rainy periods in Washington States, horses
often develop severe irritations in their lower extremities especially where the
hair-covered skin joins to the hooves. This skin area can develop irritations, infections
and bleeding. During experiments to heal such irritated skin with creams containing copper
peptides, the application of the copper-peptide cream was often imprecise due to movements
of the horses and the cream were generously applied to the lower skin of the leg and part
of the upper hooves. While the creams were observed to rapidly heal the skin areas, we
also unexpectedly observed that damaged hooves appeared to improve markedly in health.
Later, we experimented with more controlled application of the copper peptide creams into
cracks in badly damaged hooves. We found that the copper peptide cream usually produced a
remarkable healing of the hooves and closure of the cracks.
- Since then hooves
of horses and the nails of humans are similar in terms of their biochemistry and cellular
biology, we tested the application of such copper peptide creams to damaged human
fingernails and toenails. We observed that such treatment produced in humans, as in the
horses, a remarkable improvement in nail health and growth. Such types of copper-peptides,
when applied to the nail matrix and nail bed area, enhance the process of nail growth
resulting in stronger, thicker and smoother nails. Such types of copper-peptides have
previously been found to strongly enhance the production of the protein collagen and also
accelerate the repair of damaged skin. However, since nails are primarily composed of the
hard protein keratin, it was not expected that copper-peptides would increase the
production of keratin and nail growth.
Effect of CP Nail Renewal on
Nail Growth
First Experiment |
Sex |
Finger Nail Growth with CP Nail
Renewal
(Millimeters in four weeks) |
Finger Nail Growth with Placebo
cream
(Millimeters in four weeks) |
|
|
Right Hand |
Left Hand |
Person 1 |
M |
4.2 |
2.7 |
Person 2 |
M |
3.2 |
2.1 |
Person 3 |
F |
4.3 |
3.2 |
Person 4 |
F |
3.8 |
2.9 |
Person 5 |
F |
3.9 |
2.6 |
|
|
|
|
Second Experiment |
|
Left Hand |
Right Hand |
Person 6 |
M |
2.8 |
1.5 |
Person 7 |
M |
3.7 |
2.6 |
Person 8 |
F |
4.1 |
3.0 |
Person 9 |
F |
4.1 |
2.6 |
- For Stronger, Healthier Nails
- 1. Before bed, rub a light coating of CP
Nail Renewal over your hands and rub onto your nails and cuticle areas. Healthy,
strong nails are better than any artificial coating.
- 2. Avoid prolonged wetting and drying of the fingernails.
Nails are strongest when slightly acid. Avoid exposing your nails to harsh chemicals and
alkaline conditions.
- 3. Use your hands or finger pads to do simple chores rather
than your nails. Avoid picking up objects when your fingertips may strike a hard surface -
instead slide the object off the side into your hand.
- 4. Use a pencil to dial a phone, never your finger
tips. Use a letter opener, not your fingernail, to open envelopes and packages.
- 5. Dig your nails into a bar of soap before gardening. This
will help prevent dirt from getting under the nails.
- 6. Always wear rubber gloves when doing dishes or other
"tough on the nails" jobs.
Wear regular gloves during cold weather or when doing chores which may injure the nail
tips.
- 7. Manicure your nails regularly since a smooth nail will
tear and split less.
- 8. Shape and file your nails with a very fine file. Round
the tips in a gentle curve. If you have snags or irregularities, file them daily to
prevent further breakage or splitting.
- 8. Never use metal instruments to push back the cuticle. The
metal scrapes away the protective cells of the nail surface.
- 9. If your nails are "buffed," always do this in
the same direction as the nail grows and never in a "back and forth" motion
which can cause nail splitting.
- 10. If you have severe breakage or tearing problems, nail
polish can protect the nail surface. Nail polishes containing nylon fibers can add
strength and protection to fragile nails.
- 11. If your natural nails are fairly long and strong, but
tend to break off at a certain length, you may be helped by having a fiberglass overlay
applied to them. In this procedure a light layer of fiberglass is brushed over the natural
nail. This coating creates a stronger, better protected nail which is less prone to
breakage. Fiberglass overlays require re-doing about every two weeks.
- 11. Use nail polish remover as infrequently as possible
since it dries and damages the nails.
- 12. Daily biotin (2.5 mg a day) may help your nails, but do
not add biotin if you are pregnant.
- 13. Some people feel that one pack of Knox gelatin a day
helps their nail health.
-
- EMU-OIL, skin moisturizer
- Ingredients: peroxide-free
emu oil supplemented with ubiquinone, 7-keto DHEA, and mixed tocotrienols
- Many skin moisturizers sold by cosmetic companies cause
long-term damage to your skin. Traditional skin moisturizers are formulated from a variety
of low-cost oils and water-soluble chemicals that wet and loosen the skin's layer of outer
protective proteins and also cover the skin with fats that impede water loss. This
provides a brief moisturization of your skin but degrades the skin's protective properties
against bacteria and viruses. Such moisturizing creams are a mixture of oil and water plus
emulsifiers, stabilizers, preservatives and other chemicals. There is little evidence that
such creams have any beneficial effect on skin.
- Emu Oil-S for Skin is very similar in composition to human
skin oils and acts to replenish skin lipids.
Methods of Skin
Moisturization
Method |
How method works |
Time to be effective |
Problems |
Copper-Peptides |
Mimics natural repair
Repairs skin barrier
and increases the
skin's proteoglycans and GAGs |
About 2 to 3 weeks |
None |
Waxes and greases |
Heavy oils such as
petrolatum seal skin surface to water loss |
Immediate |
Greasy |
Skin Oils |
Light oils such as
sesame oil seal skin surface to water loss |
Immediate |
Not as durable as waxes and greases |
Cosmetic
moisturizers |
Mixtures of oils, water, and surface active chemicals used
to open skin barrier and
hydrate skin proteins |
One day |
Acts like irritant
Loosens protective skin barrier
Skin more susceptible to infection |
- Lipids and fats in the skin provide the epidermal barrier to
transcutaneous water loss. These lipids in the upper skin area called the stratum corneum
are arranged in layers called lamellae. The lower skin layers contain more typical fats
such as triglycerides and phospholipids while the upper layers have more ceramides,
cholesterol and free fatty acids.
- While lipid replenishment methods are still being developed
by dermatological scientists, emu oil is already a very good natural oil for lipid
replenishment. It comes from small ostritch-like bird.
- Australian aborigines discovered the benefits of emu oil
many thousands of years ago and used its helpful properties on damaged and sunburned skin.
The fatty acid composition of human skin oil and emu oil are very similar. In both oils,
mono-unsaturated oleic acid is the most prevalent, then palmitic acid, followed by the
essential fatty acid, linoleic acid. This may be the reason for the positive actions of
emu oil on human skin. Skin researchers at the University of Texas Medical School in
Houston reported that emu oil at up to 100 % concentration in lotions to be nonallergenic,
non-comedogenic, have low irritation potential, and to be bacteriostatic.
- While scientific studies on emu oil are just beginning, emu
oil has been traditionally used help alleviate discomfort of arthritis, shingles, eczema,
psoriasis and other inflammatory conditions.
- Replacement of key skin lipids often
accelerates skin repair and can be a helpful treatment for dry skin and eczema. Also,
conditions such as burns and psoriasis often benefit from emu oil.
- EMU OIL S Lipid Replenisher for Skin is a
peroxide-free emu oil supplemented with Ubiquinone, 7-keto DHEA, mixed isomers of natural
tocotrienols, and mixed isomers of vitamin E.
- Tocotrienols and Skin Health
- Topically applied tocotrienols selectively accumulate in
skin and serve to protect it against ultraviolet damage and oxidation. (Traber et al
1997). In rats it was found that UV radiation significantly reduced vitamin E
concentrations after 29 minutes of UV exposure, but in skin treated with tocotrienols the
vitamin E concentrations were 7 to 30-fold higher after the radiation.
7-Keto DHEA and Skin Health
- 7-keto DHEA is a safer metabolite of regular
DHEA (dehydroepiandrosterone), a natural hormone that improves skin lipid production.
7-Keto DHEA is one of more than 150 metabolites of DHEA , a precursor hormone that
is produced by the adrenal gland and source of many other hormones, including the sex
hormones estrogen and testosterone. Unlike regular DHEA, 7-Keto DHEA is not converted into
either estrogens or testosterone but still has DHEA's other beneficial actions.
In recent controlled studies, 7-keto DHEA has been shown to improve sense of
well-being, immune and mental function, and muscle tone in middle aged men and women.
- DHEA levels peak at age 25, then gradually decline. By age
60, DHEA levels are 30% or less of those in young adults. DHEA is also essential for
proper sebaceous gland functioning and the production of skin oils. Much of the increase
of dry skin with age is due to the decease in DHEA levels in the skin. (Sourla et al).
- Schwartz and Pashko (1996) reported that
"topical application of DHEA on mouse skin inhibits skin tumor promotion."
DHEA aids the skin's superoxide defense and this may explain its ability to prevent
skin cancer and papillomas (benign tumors). DHEA also keeps some chemical carcinogens from
binding to DNA. According to researchers at the Fels Research Institute and Temple
University, cancers just do not started if enough DHEA is present.
- Studies show that DHEA is readily
absorbed by skin when applied topically. Topically applied DHEA helps protect the skin's
delicate blood vessels. Researchers reported that when DHEA was applied after a serious
burn, the blood vessels underlying the burned area are protected and the skin is retained
instead of peeling off.
- Ubiquinone
and Skin Health
- Ubiquinone is an oxidative reduction agent that functions in the energy-producing electron transfer chain in the
mitochondria of cells. Ubiquinone also serves as an important lipid-soluble antioxidant in
the skin and other organs protecting against free radical damage from peroxides that
damage collagen and elastin, which produces a loss of elasticity in the skin and wrinkle
formation. Animals fed Ubiquinone have lower cancer rates. Ubiquinone discoverer,
Dr. Karl Folkers suggested that Ubiquinone might control cancer either by facilitating
antibody synthesis or by counteracting tumor cell functioning. His ideas were based on
case reports of unexpected or unusually long survival for cancer patients who were
using Ubiquinone for cardiac problems.
- EXFOL-CREAM, salicylic acid 2%
- Purified water, aloe vera gel, squalane, octyl palmitate,
PEG-stearate, glycerol stearate, safflower oil, salicylic acid, stearic acid, cetyl
alcohol, allantoin, diazolinydinyl urea, methylparaben, propylparaben, bronopol,mixed
(alpha, beta, gamma, delta) tocopherols, mixed (alpha, beta, gamma, delta) tocotrienols,
vitamin D.
- EXFOL-SERUM, salicylic acid 2%,
without lipids
- Purified water, aloe vera gel, salicylic acid,
hydroxyethylcellulose, allantoin, polysorbate-20.
If you have acne problems - the best for
scar reduction are the lipid-free products - CP Serum with Copper Peptides and Exfol Serum
- an aqueous salicylic acid serum.
- GENTLE CLEAN, cleanser for very
sensitive, damaged skin and valuable skin
- Gentle Clean is a cleanser for skin that is sensitive,
fragile, dry, itchy, damaged, or valuable skin. The cleanser was specifically formulated
to clean the fragile skin of cancer patients after radiation or chemotherapy. Most
cleansers cause damage to very fragile and damaged skin. Gentle Clean combination of an
effective but very mild cleanser is especially appropriate for persons with dry skin,
eczema, allergy-prone skin, psoraisis, diabetes or those recovering from cancer therapy.
However, even if your skin is healthy but you consider your skin to be very valuable, this
very mild cleanser will help clean and protect your skin.
- Gentle Clean was developed as a cleaning agent for very
sensitive and damaged skin and has been field tested for four years. Nurses and physicians
report that the cleanser works very well on sensitive and fragile skin such as which
occurs with eczema, in the bedridden, or after cancer therapy. Some nurses and physicians
have told us that they think the cleanser has healing properties but we believe that the
very careful preparation of the product produces the good results.
- Many soap and
cleansers not only remove surface dirt and oils, but they actually damage the skin by
destroying its natural protective "Acid mantle", the skin's lipid and
antioxidant barrier. This damage leads to the generation of more skin-damaging free
radicals and creates a dry, flaky skin which stimulates the production of more oil.
- Gentle Clean
works well for skin cleaning during exfoliation for skin renewal. It is is a good cleaning
system for persons as risk for skin damage such as those with eczema, psoriasis, or
diabetes. Fragile skin can literally be dissolved by strong soaps.
- The clear,
translucent cleansing bars contain no harsh detergents, caustics, glycerin, or
"flash" foaming agents. The pH of 7.8 is near neutrality in contrast to the very
basic pH of most soap and skin cleansers.
- Customers tell us
that the bar works very well to removing mascara and other color cosmetics
GLYCOLIC-8, glycolic acid 8%
- PROTECT & RESTORE , renewing
your skin's youth
- Protect & Restore is the strongest skin regenerating (with published, credible, scientific
proof of skin renewal) skin care product available. P&R has is much stronger than the
only two other skin regenerating copper peptide product lines available. Protect & Restore has between 8.8 and 18.7 more skin regenerating copper peptide than
various products in the very excellent Neutrogena Visibly Firm skin product line and and
ProCyte Neova skin product line.
- Skin regenerating copper-peptides aid
the skin's mechanisms of skin renewal while enhancing the skin's protective barrier,
anti-oxidant defenses, and sun protection. Thousands of customers have told us that
the cream enhances facial beauty by stopping breakouts, removing blemishes, improving skin
elasticity, firmness, and texture while reducing wrinkles. It also helps to reduce
excessive skin redness after the use of retinoic acid or alpha hydroxy acids, and improves their natural skin color (some women say this is an
"extra glow"). Protect & Restore often eliminates the need for moisturizers. Four independent,
published clinical studies at the University of California have proven that Protect & Restore has both skin repair and anti-inflammatory
properties and is hypoallergenic.
- P&R Classic Skin Renewal
Cream
This cream has a slipping agent to improve the spreadability of the
cream. Women who have had difficulty with creams containing high Retinol and/or Oil
of Lavender are reporting good results with this cream.
Product Ingredients: Purified water, squalane, octyl palmitate,
glycerol stearate, PEG-100 stearate, cetyl alcohol, copper-peptides (aqueous mixture
of hydrolyzed soy protein and copper chloride), myristyl ether proprionate, stearic acid,
allantoin, diazolinydinyl urea, methylparaben, propylparaben, mixed tocotrienols, mixed
tocopherols, 7-keto DHEA, coenzyme Q-10.
- P&R with High Retinol and
Oil of Lavender
This version has a high level of Retinol and Oil of
Lavender and is our most potent skin renewal and anti-wrinkle cream. It is our most
re-ordered P&R. Many people say it is the best skin cream they ever used and that the
cream rapidly improves skin color and health while stopping acne flare-ups. Several people
with unresponsive cystic acne have reported a clearing of long-term acne in a little as
one week. It is good for scar ands stretch-mark reduction. On the other hand, in some
people the cream can lead to an acne outbreak. In general, do not use this cream if you
are under age 25, or have problems with other high Retinol products (such as Neutrogena's
"Retinol(TM)") or with Oil of Lavender. Some women who had problems with this
cream are reporting very good skin improvement results with the non-retinol P&R
versions.
- The oil of lavender has
soothing effects on the skin. Oil of Lavender was used on wounds in ancient Greece and
Rome over 2,000 years ago. Today it is widely used in clinical wound-treatment products.
In one placebo-controlled blinded study of 635 women, it was found that the application of
oil of lavender to the outer birth canal resulted in much less pain and discomfort after
childbirth. Do not use if you are sensitive to Oil of Lavender.
- Product Ingredients: Purified water,
squalane, octyl palmitate, glycerol stearate, PEG-100 stearate, cetyl alcohol,
copper-peptides (aqueous mixture of hydrolyzed soy protein and copper chloride), myristyl
ether proprionate, stearic acid, allantoin, diazolinydinyl urea, methylparaben,
propylparaben, oil of lavender, mixed tocotrienols, mixed tocopherols, 7-keto DHEA,
coenzyme Q-10.
- P&R Day Cover
P&R Day Cover is designed as a daytime replacement
for sun protective creams with dangerous chemical sunscreens. This cream contains a high
level of natural ultraviolet absorbers such as squalane, peptides and nucleotides that
have been protecting mammalian skin for over 100 million years. We feel these are far
safer than the dangerous chemical sunscreens in cosmetics that cause allergies, skin
irritations, and may increase your risk of major cancers. The cream still significantly
helps skin repair.
Product ingredients
: purified water,
squalane, octyl palmitate, glycerol stearate, PEG-100 stearate, cetyl alcohol, myristyl
ether proprionate, polypropylene glycol, hydrolyzed soy protein, stearic acid, allantoin,
cupric chloride, diazolinydinyl urea, methylparaben, propylparaben, oil of lavender, mixed
tocopherols, mixed tocotrienols, 7-keto DHEA, coenzyme Q-10.
-
- Protect & Restore Suntanning
Lotion, suntan science, faster, healthier suntanning, without toxic sunscreen
- Protect & Restore Suntanning
Lotion contains patented (US Patent 5,698,184) copper-peptide complex that acts as a
superoxide dismutase that can help de-toxify oxygen radicals produced by ultraviolet rays
on the skin's surface. Creams containing superoxide dismutase activity have been proven to
help protect skin during ultraviolet radiation exposure. (Reference: Miyachi
Y, Imamura S, Viwa G. Decreased skin superoxide dismutase activity by a single exposure of
ultraviolet radiation is reduced by liposomal SOD pre-treatment. J Invest Dermatol 1987;
87:111-2). P&R Suntanning Lotion also contains other anti-oxidants
such as vitamin E, tocotrienols and Ubiqunone.
-
In addition, the lotion contains titanium dioxide (a reflective sunblocker), and a high
level of squalane and other proven skin protective agents such as allantoin, aloe vera,
glycerol stearate and octyl palmitate. Squalane is the skin's most important protective
lipid and declines from levels of 11% in teenager's skin to less than 5% in adults after
age 20. The cream components such as squalane, peptides, and allantoin are all
natural skin components that have high absorption in the ultraviolet range to help protect
the skin. P&R Suntanning Lotion does not contain chemical sunscreens such as
benzophenone or oxybenzone (benzophenone-3) which are free-radical generators and may
increase cancer risks.
- The
composition of Protect & Restore Suntanning Lotion
is: Purified water, aloe vera gel, squalane, octyl palmitate, PEG-100 stearate (glycerol
stearate and PEG-100 stearate), polypropylene glycol, cetyl alcohol, copper peptides
(hydrolyzed soy protein + copper chloride), myristyl ether proprionate, stearic acid,
allantoin, titanium dioxide, diazolinydinyl urea, methylparaben, propylparaben, mixed
natural tocopherols (alpha, beta, gamma, delta isomers), mixed natural tocotrienols
(alpha, beta, gamma, delta isomers), 17-keto DHEA, ubiquinone, melatonin, herbal
fragrance, retinyl palmitate, ergocalciferol, bronopol. (Copper peptides are formed when
the cupric chloride and hydrolyzed soy protein are mixed in water during the preparation
of the Suntanning Lotion.)
- Tocotrienols and Skin Health
- Topically applied tocotrienols selectively accumulate in
skin and serve to protect it against ultraviolet damage and oxidation. (Traber et al
1997). Diet alone cannot supply adequate amounts of tocotrienols for skin protection. In
rats it was found that UV radiation significantly reduced vitamin E concentrations after
29 minutes of UV exposure, but in skin treated with tocotrienols the vitamin E
concentrations were 7 to 30 fold higher after the radiation.
- 7-Keto DHEA and Skin Health
- 7-keto DHEA is a safer metabolite of regular
DHEA. 7-Keto DHEA is one of more than 150 metabolites of DHEA (dehydroepiandrosterone), a
precursor hormone that is produced by the adrenal gland and is the source of many other
hormones, including the sex hormones estrogen and testosterone. Unlike regular DHEA it is
not converted into either estrogens or testosterone but still has DHEA's other beneficial
actions. In recent controlled studies, 7-keto DHEA has been shown to improve
sense of well-being, immune, mental function, and muscle tone in middle aged men and
women.
- DHEA levels peak at age 25, then gradually decline. By age
60, DHEA levels are 30% or less of those in young adults. DHEA is essential for proper
sebaceous gland functioning and the production of skin oils. Much of the increase of dry
skin with age is due to the decease in DHEA levels in the skin. (Sourla et al).
- Schwartz and Pashko (1996) reported that
"topical application of DHEA on mouse skin inhibits skin tumor promotion."
DHEA aids the skin's superoxide defense and this may explain its ability to prevent
skin cancer and papillomas (benign tumors). DHEA also keeps some chemical carcinogens from
binding to DNA. According to researchers at the Fels Research Institute and Temple
University, cancers just do not start if enough DHEA is present.
- Studies show that DHEA is readily
absorbed by the skin when applied topically. Topically applied DHEA helps protect the
skin's delicate blood vessels. Researchers reported that when DHEA was applied after a
serious burn, the blood vessels underlying the burned area are protected and the skin is
retained instead of peeling off.
- Ubiquinone and Skin Health
- Ubiquinone is an oxidative reduction agent that functions in
the energy-producing electron transfer chain in the mitochondria of cells. It also serves
as an important lipid-soluble antioxidant in the skin and other organs. It protects
against free radical damage from peroxides that damage collagen and elastin, thus
protecting against a loss of elasticity in the skin and wrinkle formation. Animals fed
ubiquinone have lower cancer rates and its discoverer, Dr. Karl Folkers, suggested
that ubiquinone might control cancer either by facilitating antibody synthesis or by
counteracting tumor cell functioning. His ideas were based on case reports of
unexpected or unusually long survival for cancer patients who were using ubiquinone for
cardiac problems.
- Melatonin and Skin Health
- Melatonin is a hormone connected with sleep patterns and
also a powerful human antioxidant that protects against UV radiation. Researchers at the
University of Zurich have shown that topically applied melatonin gives excellent
protection against sunburn if applied before sun exposure and also may have role in
repairing burned skin. In small amounts, melatonin causes skin cells to proliferate.
People with psoriasis and atopic eczema have low melatonin levels.
- The Skin Biology Approach to
Sensible Suntanning
- 1. Before suntanning apply Protect & Restore Suntanning Lotion as a
thin coating prior to suntanning. A small amount of water may be used to help spread the
cream. This is a skin regenerating cream with titanium dioxide and high levels of
anti-oxidants.
- 2. After suntanning, re-apply P&R
Suntanning Lotion or P&R Body Lotion. THIS IS CRITICAL - USE COPPER PEPTIDE SKIN
REGENERATING CREAMS BEFORE AND AFTER SUNTANNING.
- 3. If you
have a tendency to sunburn or plan an extended time in the sun,
use a reflective sunscreen such as zinc oxide or titanium dioxide. One acceptable
sunblocker is Clinique's SPF-25 Special Defense Sunblock which is chemical sunscreen-free.
- 4. Moderate suntanning ( 30 minutes
maximum per day ) over a number of days produces the best results. Suntanning slowly
produces pigment (melanin) in the skin. It takes about three days to induce significant
melanin in your skin. Melanin blocks ultraviolet rays and also serves as a powerful
anti-oxidant. In addition, the skin's natural defenses against oxygen radicals include
other anti-oxidants such as Vitamin E and beta-carotene, and the copper-containing
protein, superoxide dismutase, all of which de-toxify oxygen radicals and reduce skin
damage.
- 5. Suntanning also thickens the skin
and this provides further protection against sun burns but this thickening takes about
three weeks. Skin thins with age and is thicker when we are young. But again, go slow!
- 6. Remember, excessive sun exposure
can overwhelm the protective systems in the skin, causing skin damage that produces skin
peeling and other types of damage. Dr. Lester Packer (University of California,
Berkeley) has published extensively on the role played by antioxidants such as Vitamin
E and skin protection. His research found that after absorbing in the UVB
radiation from sunlight spectrum, vitamin E is transformed into a free
radical (tocopheroxyl) which can regenerate back to vitamin E (tocopherol) via
reaction with the skin's vitamin C (ascorbic acid). Packer's hypothesis is
that as ultraviolet radiation dosage is gradually increased, these two antioxidant
defenses of the skin are overwhelmed. Then free radicals begin to form in the skin and
cause various types of cellular damage, including lipid peroxidation and oxidative
modification of skin proteins and cellular DNA. Packer has measured the depletion of
cutaneous lipid soluble antioxidants (such as Vitamin E) after ultraviolet radiation
of the skin. For example, 45 minutes of exposure to the noon-day sun can lower the skin's
protective vitamin C levels by 80%. and also markedly lower other protective skin
anti-oxidants such Vitamin E and beta-carotene. Packer also
finds that sunblockers reduce this depletion of dermal antioxidants.
- 7. Take 2 milligrams of copper 2+
daily. Do this even if you are taking a multimineral supplement since most such
supplements have so much zinc that they drive out copper 2+. The extra copper 2+ will
activate more superoxide dismutase, your primary anti-oxidant defense.
- The extra copper 2+ will also activate
more copper-requiring tyrosinase. The enzyme converts tyrosine into melanin, the skin
pigment. It is impossible to effective tan with adequate copper 2+ in your skin.
- 8. High quality sunglasses that absorb ultraviolet rays
should be worn for eye protection.
- "Inside-Outside" Sun
Protection
-
If you tend to sunburn or plan an extended time in sunlight, take anti-oxidant
supplements. Studies have found that both the topical application of anti-oxidants and the
ingestion of supplemental anti-oxidants reduce sun damage.
-
The following supplements have been recommended by skin researchers. (Source: Drug and
Cosmetic Industry, September 1997, pages 52-55 and December 1997, pages 40-44.
- Why
Protect & Restore Is Better than Cortisone on Irritated Skin
-
Protect & Restore's copper-peptide reduces the need for the use of corticosteroids for
skin dermatitis. Corticosteroids (such as cortisone) produce damaged and thinned skin
(often 50% thinner) by inhibiting the natural skin repair processes. Use of
corticosteroids produces a vicious cycle requiring more corticosteroid use due to more
irritations from the weakened skin. The use can promote diabetic conditions, thymus
involution, immune suppression, the spread of cancers, bone damage, and cataracts. It is
estimated that 5,000 hip replacements yearly in Canada are due to overuse of
corticosteroids.
-
During inflammation, the skin is damaged by immune cells that release toxic oxygen
radicals into the damaged area. The purpose of these oxygen radicals is to kill invading
bacteria after wounding but often the oxygen radicals are released in the absence of any
bacteria. Cortisone and corticosteroids act by killing the immune cells to stop oxygen
radical release but this also kills the immune cells that release the skin repair growth
factors and hence stops skin repair which ultimately leads to a thinned and damaged skin.
-
Copper-peptides, on the other hand, directly detoxify the oxygen radicals. They also
transfer copper to superoxide dismutase (SOD), the skin's primary anti-oxidant protein,
which activates the more skin's SOD (normally only about 30% of SOD is active) which
further increases the removal of oxygen radicals. Also, the copper-complexes have been
shown to strongly stimulate the skin's repair systems and improve healing and skin
renewal. The above mentioned nickel allergy study demonstrated both the anti-inflammatory
and skin repair properties of copper-peptides. (Zhai, Chang, Singh, and Maibach, "In
vivo nickel contact dermatitis: human model for topical therapeutics", Contact
Dermatitis Vol. 40, pp. 205-208, 1999.)
Protect & Restore |
Clinically-proven to speed skin renewal |
Rebuilds collagen and elastin for a firmer,
more elastic skin |
Activates skin remodeling to remove damaged
proteins |
Activates the skin's natural anti-oxidant
defense |
Better skin blood circulation improves skin
color |
Helps reduce irritation from retinoic acid and
hydroxy acids |
Improves skin uniformity and "glow" |
Reduces itching and flaking of the skin |
Hypo-allergenic |
Will not clog pores |
Ultraviolet protection |
Anti-inflammatory action |
Retinol versions to increase wrinkle reduction |
Glycolic-8, Exfol
Cream/Serum, Tri-Reduction Glycolic Exfoliator |
Gently exfoliates damaged skin |
The best of the alpha hydroxy acid for skin
renewal |
Rebuilds skin collagen and elastin |
Removes skin imperfections |
Increases skin firmness and elasticity |
Age Range |
Skin Condition |
Skin Problems |
Common
Treatments |
Best P&R choices |
18-24 |
High oil production
Collagen/Elastin
in balance
Thick elastic skin
Hormonal Increases
Rapid skin repair
Skin replaced every
three weeks |
Acne from High Oil
Too many cosmetics used |
For Acne - Retin-A ® (marchio registrato),
Differin, Accutane |
1. Classic - no retinol |
25-45 |
Some Acne
Dryer Skin
Slower skin repair
Collagen/Elastin
breakdown starts
Decreased skin pheromones |
Women - eczema from childcare, wrinkles start |
Retin A
Hydroxy Acids |
1. Classic - no Retinol |
|
|
Rosacea |
Antibiotics such as MetroGel and Sulfacet-R
Sometimes Accutane |
1. Classic plus
Gentle Clean
to reduce flare-ups,
Sometimes eliminates rosacea |
|
|
Chronic Cystic Acne |
Retin A |
1. High Retinol
Sometimes Clears Acne |
45-70 |
Thinning Skin
Slower repair
Collagen/Elastin
breakdown high
Skin replacement slows to every nine weeks
Decreased skin pheromones |
Dry Skin, Wrinkles
Loss of Elasticity |
Retin-A ® (marchio registrato), Hydroxy Acids
Peels, Laser-Resurfacing |
1. High Retinol |
|
|
Skin Lesions Common |
Remove with Peels, Lasers |
Remove with mix of
High Retinol
and Glycolic-8 applied to lesion |
over 70 |
Thin Skin
Inadequate Skin Repair
Collagen/elastin
breakdown severe
Decreased skin pheromones |
Poor healing
Small sores |
|
High Retinol |
- TRI-REDUCTION, copper peptides to
aid in reduction of scars, acne scars, skin tags, stretch marks and sun damage lesion
- TriReduction P&R Basic
Ingredients: Purified water, squalane, octyl palmitate, glycerol
stearate, PEG-100 stearate, cetyl alcohol, copper peptides (hydrolyzed soy protein
chelated to copper chloride), propylene glycol, stearic acid, allantoin,
diazolinydinyl urea, methylparaben, propylparaben, tocopheryl acetate, menthol.
- TriReduction P&R with Retinol
Ingredients: Purified water, squalane, octyl palmitate, glycerol
stearate, PEG-100 stearate, cetyl alcohol, copper peptides (hydrolyzed soy protein
chelated to copper chloride), propylene glycol, stearic acid, allantoin, diazolinydinyl
urea, methylparaben, propylparaben, retinol acetate, tocopheryl acetate, menthol.
- TriReduction Glycolic Exfoliator
Product Ingredients - Purified water, glycolic acid (14%), glycerol
stearate, PEG-100 stearate, octyl palmitate, safflower oil, stearic acid, cetyl alcohol,
sodium hydroxide, methylparaben, propylparaben.
- Copper peptides activate the system that removes damaged proteins and
scars from the skin.
- During skin remodeling, the old damaged protein is removed
and replaced with new collagen and elastin fibers. This removes scar tissue and restores
skin elasticity and reduces wrinkles.
- Exfoliating creams, and their stronger versions used as
"chemical peels" have long been used to reduce scars. Likewise, Retin-A ® (marchio registrato)
(retinoic acid) reduces scars but can be quite irritating to the skin.
- The entry of "real" skin repair creams into skin
care will also change methods of scar treatment.
- At Skin Biology,
we have had many customers report very good results on skin lesion removal or reduction of
scars, sun damage marks, skin tags, acne scars, some types of moles and flat warts and
stretch marks of pregnancy. Most often the skin repair creams are used in combination with
the glycolic acid and/or retinoic acid (Retin-A ® (marchio registrato). This is a much lower cost method than
laser treatments or silicone sheets and less irritating than retinoic acid alone. This is
a very simple, low cost, safe and painless method that often works surprisingly well.
- Dermatologists
have long used both glycolic acid and retinoic acid to reduce scars and skin
imperfections. The addition of copper-peptide creams improves the overall process.
- Deep chemical
peels are often recommended for scars, but if the dermatologist or esthetician is not
highly skilled, this is often unsatisfactory and can produce further scarring. We get many
telephone calls from people who have had deep chemical peels for scars and ended up with
worse scarring than their initial scars or calls about laser treatments that left
permanent skin damage.
- Use of Copper-Peptide creams with
Glycolic Acid and Retinoic Acid
- To use this
method to reduce skin lesions, mix the two creams (an exfoliating cream and a
copper-peptide skin repair cream) together in a cup or bowl, then apply the mixture to the
scar or lesion with your finger. Results should be evident in about one month as a
reduction in the area and thickness of the lesion. After a week, you may also notice a
slight flaking of skin around the periphery of the lesion. This is usually followed by a
shrinking and thinning of the skin lesion which is significant after one month.
- For facial acne
scars, either use a mixture of TriReduction P&R Basic or Trireduction P&R with
Retinol. If you are under age 25 or have acne flare-ups, stick to TriReduction P&R
Basic. With your fingers, just rub a small amount of the cream mixture right on the acne
scar.
- Before starting
this procedure, make an accurate drawing of the skin lesion(s) on a piece of paper so you
can monitor the progress of the treatment.
- If a more active scar
removal is desired, add retinoic acid (Retin-A ® (marchio registrato) to the mixture or put retinoic acid on the
skin lesions in the morning and the mixture of glycolic acid and skin repair cream in the
evening.
Scar or Lesion Reduction with
P&R (BioHeal), Glycolic Acid, and Retinoic acid
System |
Advantages |
Problems |
TriReduction P&R Basic and
TriReduction P&R with Retinol |
Reduces many small scars and lesions |
May need stronger skin renewal |
12 to 15% Glycolic acid creams |
Reduces many small scars and lesions |
May need stronger skin renewal |
20 to 30% Glycolic acid peels |
More effective scar removal |
May cause burns and more scars
Should be done by experienced dermatologist
Expensive |
Retinoic acid |
Reduces many small scars and lesions - Inexpensive |
Can be very irritating |
TriReduction P&R creams plus
TriReduction Glycolic Exfoliation Cream |
More effective scar reduction
Inexpensive |
None |
In morning -
Use 0.1 to 0.25% retinoic acid
In evening - use
TriReduction P&R creams plus
TriReduction Glycolic Exfoliation Cream |
Much more effective scar reduction
Inexpensive |
Can be irritating if overused |
Our strongest copper-peptide product cream is TriReduction
P&R with Retinol. TriReduction P&R Basic does not have the retinol and is best for
areas where acne breakouts may be a problem. If you are under age 25 or have acne
flare-ups, then for facial use we recommend using the TriReduction P&R Basic.
Products to Use for Reduction
or Removal of Skin Scars and Lesions
Use and person's age |
Product to Use |
Comments |
General scar, sun damage and lesion reduction |
Use TriReduction P&R with Retinol and TriReduction
Glycolic |
TriReduction P&R with Retinol may cause acne in
younger persons |
If under age 25, for facial
scars and lesions |
Use TriReduction P&R Basic and TriReduction
Glycolic
or CP Serum and Exfol Cream/Serum |
Many young people (under age 30)
cannot tolerate Retinol |
If over age 25, for facial scars and lesions but problems
with breakouts |
Use TriReduction P&R Basic and TriReduction
Glycolic
or CP Serum and Exfol Cream/Serum |
Best for persons who cannot tolerate Retinol in
creams |
Comparison of
Scar and Lesion Reduction Methods
Method of scar
reduction |
Cost |
Advantages |
Time to
Noticeable Improvement |
Potential
Complications |
Skin regeneration accelerators such as TriReduction |
$30 to $60 |
Low Cost
Ease of Use |
One Month |
None |
Glycolic/Salicylic acid |
$30 to $60 |
Low Cost
Ease of Use |
One Month |
Mild skin irritation |
Retinoic acid |
$100 to $300
($50 to $100 products,
$50 to $200 dermatologist appointment) |
Low Cost
Ease of Use |
One Month |
Skin irritation can be severe |
Mixtures of Copper-Peptides,
Glycolic/Salicylic acid, |
$30 to $60 |
Better results with less irritation than glycolic acid
alone |
One Month |
None |
Mixtures of Copper-Peptides,
Glycolic/Salicylic acid,
and retinoic acid |
|
Better results with less irritation than glycolic or
retinoic acid alone |
One Month |
Mild skin irritation |
Plastic sheets |
$100 to $400 for plastic sheets plus
$200 dermatologist appointment |
No pain |
Two to four months |
Modest results -
takes months |
Scar Subcision |
$300 to $500
dermatologist costs |
Often works on severe localized scars |
Two to four months |
|
Laser resurfacing |
$1,000 to $4,000 |
Good with
skilled dermatologist
or esthetician |
Two to four months |
Painful
Local Pigmentation
More scarring |
Deep peels |
$500 to $3,000 |
Good with
skilled dermatologist
or esthetician |
Two to four months |
Painful
Local Pigmentation
More scarring
Skin Infection |
Dermabrasion |
$1,000 to $3,000 |
Good with
skilled dermatologist
or esthetician -
Sometimes good for deep scars |
Two to four months |
Painful
Local Pigmentation
More scarring
Skin Infection |
Microdermabrasion |
$1,000 to $3,000 |
Good with
skilled dermatologist
or esthetician |
Two to four months |
Milder than dermabrasion -
Less Painful
Local Pigmentation
Sometimes scarring |
"At-Home" Skin
Renewal Methods
Method |
Works by |
Effects |
Used Clinically? |
Problems |
Copper-peptides
(Protect & Restore,
Blue Copper,
Neova, A-Copper Moisturizer) |
Triggering the skin's natural renewal mechanisms |
1. Rebuilds skin protective barrier
2. Increases collagen and elastin - more than vitamin C
3. Increases water-holding proteoglycans
4. Rebuild blood microcirculation
5. Activates removal of damaged skin proteins
6. Activates skin's main antioxidant protein -
dismutase superoxide
7. Increase apocrine gland size and may increase sexual pheromone attractants |
Yes
1. Wound healing
2. After skin resurfacing
3. For hair transplants |
None known |
Vitamin C creams and patches |
Vitamin C helps collagen synthesis and acts as antioxidant |
1. Increases collagen production but less than
copper-peptides |
No, effects on skin are too small |
Must be very acid (pH=2.5) for best effects |
Furfuryladenine creams
(Kinerase and Kinetin) |
Plant chemical that improves skin texture, reduces
blotchiness, and reduces fine wrinkles |
Unknown |
No |
None but much less active than copper peptide creams (see
below) |
Retinoic acid
(Retin-A ® (marchio registrato) |
Acts by irritation and
cell differentiation actions |
1. Triggers collagen and elastin synthesis but less than
copper-peptides
2. Increases skin thickness |
Yes, for acne and
skin renewal |
Very irritating
Produces skin redness |
Hydroxy acids |
Act by irritation
that stimulates new
skin repair |
1. Increases collagen and elastin synthesis
2. Increases skin thickness |
No |
Effects are slow
Can be irritating |
- PRODUCT USE
-
We generally recommend starting with P&R Classic. If you then want more skin
renewal and anti-wrinkle activity, try the low Retinol P&R. If these agree with your
skin, then try high Retinol P&R which is our strongest cream and also good for
reducing scars and stretch marks.
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Versions with Retinol which reduces collagen and elastin breakdown which increases after
age 30 and increases the wrinkle reduction but also may increase acne outbreaks. Version
High Retinol is our most potent cream while Low Retinol has a 90% reduced Retinol content.
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Our records indicate that about 5% of women (mainly under age 30) have difficulty with
P&R version High Retinol and this could be as high as 10% because not everyone
complains. However, P&R#3 is also our most re-ordered skin cream. Some women who had
difficulty with P&R version High Retinol are reporting very good skin results with the
non-retinol versions and are recommending these to their friends
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The differences in the versions are actually quite minor but the various versions often
have greatly different actions on the skin of different persons. For example, P&R
with Hight Retinol (vitamin A) and Oil Of Lavender has strong skin repair and
remodeling properties and works extremely well for some people, but other persons have
difficulty with this version. Also, many people have previous sensitivities to
various oils, fragrances, and other cream components. The need for different versions of P&R is similar to the use of
different versions of Retin-A ® (marchio registrato) or Hydroxy Acids used for people with different skin types.
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In our four clinical studies, we actually ran three different P&R versions through
every test but only published data on the standard version. By testing various P&R
formulations in this manner, we determined which cream components were critical for skin
repair and which were not. For example, we found that various anti-pain agents such as
camphor and menthol had no effect on skin repair. Likewise different fragrances had no
effect on skin repair. Copper chloride and copper sulfate also make no difference - the
copper ion ion the cream is associated with the peptide as a complex. Minor changes in the
oil constituents also did not significantly alter skin repair.
- In recent months, many of of our customers
have told us that they are seeing great results on their skin by applying a thin coating
of CP Serum in the morning covered by a small amount of Emu Oil as a moisturizer. Then
before bedtime, they apply a thin covering of glycolic/salicylic acid followed by P&R
cream.
- Post Procedure Treatment after
Skin Peels, Dermabrasion, and Laser Resurfacing
- 1. CP Serum applied to the skin in within 2 hours after the
procedure.
- 2. The client is given a 1 oz vial of CP Serum with
instructions to apply a thin coating of CP Serum daily to the healing skin.
- 3. Caution the client to just use a light coating of CP
Serum. Too often, people think more is better.
- Post-procedure treatment for
skin that remains irritated, reddened, and has new scars from the procedure
- In this situation, the treated skin is very sore and
irritated. Often burns and hyperpigmentation marks are visible. This state can exist for a
year after a procedure.
- 1. Have the client apply Emu Oil for Skin until the soreness
is alleviated.
- 2. Then have the client apply, to the affected skin, CP
Serum followed by Emu Oil on a daily basis.
- 3. Caution the client to just use a light coating of CP
Serum. A small amount of CP Serum is quite effective.
- 4. Skin recovery by this method is slow but a significant
improvement should be noted in a month. For severely burned or irritated skin, full
recovery may take several months.
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Comparison of Protect & Restore and BioHeal
- The skin repair creams come in two
versions but in terms of their skin repair potential they are similar. Protect &
Restore is formulated more for cosmetic uses and has a lighter color. Many women use it as
a morning make-up base. BioHeal is designed more for therapeutic skin repair and is
formulated with non-drug components (menthol and camphor) that help decrease pain and
itching. Both versions were tested in the clinical studies and gave similar results on
skin repair and reducing irritation.
- For skin renewal and repair, Protect & Restore is either
used alone or - if stronger skin renewal is desired - with a exfoliating cream such an
alpha hydroxy acid like Glycolic-8 or with retinoic acid (Retin-A ® (marchio registrato).
- Comparison of Protect &
Restore, BioHeal, and TriReduction
- The skin repair creams come in
three versions but they all increase skin renewal. Protect & Restore is formulated
more for cosmetic use and has a lighter color. Many women use it as a morning make-up
base. BioHeal is designed more for therapeutic skin repair is formulated with non-drug
components (menthol and camphor) that help decrease pain and itching. The TriReduction
creams are stronger and designed for "spot" use to help reduce scars, sun damage
marks and stretch marks. All versions were tested in the clinical studies and gave
fundamentally similar results on skin repair and reducing irritation.
Moisturizing Skin
- Dry skin is
caused by two problems: (1) Damage to the skin's protective barrier which produces
excessive water loss through the skin, and (2) a reduction in the concentrations of the
skin's water-holding sugars and proteins (proteoglycans and glycosaminoglycans or GAGs).
Copper-peptides act by repairing the skin barrier and raising proteoglycans and GAGs.
Waxes and oils seal the skin's surface and prevent excessive water loss. Cosmetic
moisturizers loosen the skin's protective barrier and hydrate (wet) the skin proteins but
at the expense of skin damage.
- The essentials of facial skin
care are:
- 1. A
Skin Repair Cream such as Protect & Restore, or
Neova (ProCyte) that both stimulates skin repair and activates the metalloproteases
that remove damaged skin proteins. Virtually all other "skin repair" or
"night repair" creams on the market are cosmetic company "hype" and
have no effects or very minimal effects on skin repair. Any product without independent
and published clinical studies - studies that you can readily obtain - should not be
purchased.
- 2. If you
want stronger skin renewal,
then use an Exfoliating Cream that uses glycolic/salicylic acid, an alpha hydroxy acid
(AHA). AHA's are one of the safest methods of increasing skin turnover. For significant
renewal to occur, AHA's must be at least 7% and have a pH (acidity) of 4.0 or lower.
Chemical peels with stronger AHA's (70%) speed the process, but the skin rebuilding
induced by a 70% AHA chemical peel (which is costly and may cause scarring) in 3 months
can be duplicated by a 7% AHA cream in 9 months. The glycolic acid should be at least 7% in concentration and a pH below
4.0. Be cautious with glycolic acid above 10% as it can cause burning. Glycolic acid helps
normalize skin oil production.
- 3. A
Retinoic Acid cream such as generic retinoic acid,
Tretinoin, Retin-A ® (marchio registrato), or Renova if you have excess skin oil production and acne. Reduce
retinoic acid use to fewer times per week if you become too irritated. Retinoic acid is a
very good product, but many dermatologists sell the product and tend to over prescribe
retinoic acid and under estimate irritation. Never use cortisone or corticosteroids to
reduce retinoic acid irritation. Many users of Protect &
Restore have told us that it helped reduce the irritation produced by retinoic acid.
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Retinoic acid is the acid version of vitamin A or retinol. It reverses aging effects on
skin, reduces wrinkles and mottled darkened spots and smoothes the skin. It reduces skin
oil by shrinking sebaceous glands and unclogging follicles. It also increases epidermal
thickness and stimulates the deposition of new collagen. Like AHAs, retinoic acid acts by
inducing a controlled irritation in the skin followed by the body repairing the damaged
area
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Many new versions of Retin-A ® (marchio registrato) are now appearing on the market and sold as great
improvements over Retin-A ® (marchio registrato) (retinoic acid). This is because the patents on Retin-A ® (marchio registrato) are
expiring which will sharply drop the price. If retinoic acid becomes an OTC product
available on the shelf in drugstore, the price will drop to $1 to $2 per tube. The new
retinoic acid products appearing on the market are only marginally better (if at all) than
the original Retin-A ® (marchio registrato) and are being introduced to keep a high price on the product.
- 4. A
Very Gentle Facial Cleanser. Be careful here because
many "gentle" cleansers have very alkaline pHs of 9.5 to 10.0. The pH should be
near neutrality and there should be no foaming or lathering agents in the cleanser. These
foaming chemicals only damage skin and do not help with skin cleansing. Check out our
Gentle Clean Cleansing Bar in this website.
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Also, excessively strong cleansers may wash away your sexual pheromones which are a major
component of your attractiveness to others.
- 5. For
Sun Protection, use products with reflective
sunblockers such as pure titanium dioxide and zinc oxide. Do not use micronized or
siliconized titanium dioxide or zinc oxide because they penetrate deeply into the skin
whereas, the pure forms remain on the skin's surface.
- For decades, irresponsible cosmetic
companies and a small group of very vocal, publicity-seeking, dermatologists have strongly
advocated that chemical sunscreens should be heavily applied before any exposure to
sunlight. They insisted that such sunscreen use would prevent skin
cancer and protect your health. This was despite of a lack of
any adequate safety testing of these chemicals. (It should be emphasized that most
dermatologists are much more cautious and careful.
- But do not use cosmetics with chemical
sunscreens since they are irritating, cause skin allergies, generate free radicals that
damage skin, and may cause cancer and birth defects. In 1997, Europe, Canada, and
Australia changed sunscreens to use three specific active sunscreen ingredients
-avobenzone (Parsol 1789), titanium dioxide, and zinc oxide - as the basis of sunscreens.
In the USA, the cosmetic companies have held off this policy as they try to sell off their
stockpiles of cosmetics containing sunscreens banned in other countries. Many scientists
have presented evidence that chemical sunscreens may increase your risk of cancers of the
breast, ovaries, prostrate and colon.
- Many common sunscreen chemicals have
estrogen-like effects. Such effects can increase cancers, cause birth defects in children,
and lower sperm counts in men. Margaret Schlumpf from the Institute of Pharmacology
and Toxicology at the University of Zurich, Switzerland, found that they trigger
developmental abnormalities in rats. Her research team tested six common UV screening
chemicals used in sunscreens, lipsticks and other cosmetics. All five tested UVB screens
-benzophenone-3, homosalate, 4-methyl-benzylidene camphor (4-MBC), octyl-methoxycinnamate
and octyl-dimethyl-PABA - acted like estrogen in lab tests and caused cancer cells grow
more rapidly. One of the most common sunscreens, 4-MBC, when mixed with olive oil and
applied to rat skin, caused a doubling of the rate of uterine growth well before puberty.
"That was scary, because we used concentrations that are in the range allowed in
sunscreens," said Schlumpf.
- 5. Your Color Cosmetics for facial color. Use the bare minimum that you need. They are filled
with coloring agents and metals that do nothing good for skin.
- 6. Give Your Skin a Break once a week and use nothing.
- 7. What Not to Use: Cosmetic companies want you to pile layers of their products
on your skin. Keep in mind that children have great skin and use nothing.
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Moisturizers should be used only as needed since they tend to loosen the outer skin layer.
If you use Protect & Restore, you will have a greatly reduced need for moisturizers.
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Toners and astringents may be used for removing makeup but remember that they damage skin
and increase skin oil production. Instead, try to use very mild cleansers for makeup
removal and facial cleaning.
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Do not use products containing animal collagen or elastin. They have no positive effect on
skin and only increase your chances of infection by prions that produce "Mad Cow
Disease" and other degenerative diseases.
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Most botanicals and herbs also possess many irritants, poisons, and carcinogens. This is
how they reduce their chances of being eaten by insects and other animals. The beauty of a
plant or flower has nothing to do with your skin's health.
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- GLYCOLIC ACID
- The hydroxyacids are non toxic substances found in
the human body, in the fruit, in the wine, in the milk, in the sugar reed, etc. They act
as a peeling and powerfully against the wrinkles, antiage.
The alpha-hydroxy-acids include the
glycolic acid, lactic, malic, hydroxyicaprylic, hydroxyetanoic, etc.
The beta-idroxy-acids include the
salicilic acid, citric acid.
This type of substances accelerate the
turnover of the skin, remove the lesions, restore steadiness, elasticity and have
"true" moisturizing characteristics, since they the inside.
They not only accelerate the cellular exchange
or remove the dead cells as it often hails the pharmaceutical industry but they
improve the renewal of the skin strongly, increasing the collagen, elastin and the inside
hydration, stimulating the production of proteins moisturizers and sugars, act as a
peeling and powerfully against the wrinkles, as a antiage.
The glicolyc acid is an alpha-idroxy-acid, in
fact introduces a idrossilic group tied up OH to the adjacent to carbon the group sour
COOH.
The linear formula of glicolyc acid is CH2(OH)COOH.
It has the lowest weight between
alpha-idroxyacid and therefore it has more deep and complex action on the skin.
It can be used for improving the penetration
of substances through the derma.
It is used mainly for anti-wrinkle effect: it
opposes the aging of the skin, with the use the derma returns to have the thickness and
turgidity of that of a juvenile. It stimulates the fibroplast directly and therefore the
collagen, elastin and mucopolisaccaridi that maintain the young and elastic skin. Although
it is an exfoliant, in time great thickness will be had, in fact being igroscopyc (it
absorbs water) it develops intense moisturizing action, act as a peeling and powerfully
against the wrinkles, as a antiage.
It is always necessary to ask the
personal dermatologist.
It is dissuaded for labial herpes. Whom has
used the tretinoin it has to attend at least 60
days before beginning the treatment, because the retinoic acid amplifies notably the
desire cutaneous reactions.
The effect varies according to the acidity, of
the concentration, and from the minutes of laying: more they are tall more it penetrates
in depth.
The concentration surest of the glicoly acid
seems to be 7-8% to pH 3.5 - 4. Produced to small concentration and superior pH they are
ineffective.
After having washed face and removed the sebo
from the skin using a gauze dampened with alcohol in non excessive way and without
rubbing. Then it is applied with a brush or a coton fioc, therefore it is vaporized on the
part water alcalinizzata. To avoid iperacid burns, applies each other to a partial
neutralization with trietanolammina or ammonia up to pH 3.5-4.5%, or bicarbonate of sodium
at 5%. Therefore it is washed abundantly with water. Then to apply creams to facilitate
the reconstruction of the skin and from the soothing effect. An allantoine ointment can be
useful.
It causes redness and cutaneous irritation to
the moment of the application. Then in the 24-48 following hours can appear a light
desquamation. The redness can have covered with a good cream dye.
The glicolyc acid at 50% collided not with
well (ph <1) for over 3 minutes, cause burns of 2º.
- SALICYLIC ACID
- Such types of copper peptides work best inconjuction with a
beta hydroxy acid such as salicylic acid. The hydroxy acid loosens the
scar proteins and the copper peptides help in the removal of the scar proteins. The copper
peptides also help the process of rebuilding new collagen and elastin into the skin.
Biologically effective copper-peptides help the skin to (1) regenerate new collagen and
elastin which improve skin firmness and elasticity, (2) increase the production of water
holding glycosaminoglycans which is true moisturization, (3) improve the skins blood
vessel microcirculation, (4) produce biochemical energy from nutrients in the bodys
blood supply, (5) increase the natural defense mechanism against oxidative damage, and (6)
repair damage to the protective skin barrier.
A leading dermatologist, Dr. Albert Kligman, believes that
BHAs, in particular salicylic, at concentrations of about 2%, are better than AHAs for
anti-aging and for skin exfoliation. Professor Kligman is well known in dermatology for
his research on the anti-aging actions of retinoic acid (Retin-A ® (marchio registrato). Results from Dr.
Kligman's laboratory found that the outermost stratum corneum layer is renewed after
applications of salicylic acid.
A small amount of the salicylic acid is converted into
copper salicylate, a powerful and safe anti-inflammatory. This blends skin
exfoliation with skin soothing actions. Salicylate also has ultraviolet absorbing
properties. Prof. John Sorenson has researched and written extensively on beneficial
actions of copper salicylate on skin, general health, and the anti-cancer properties of
copper salicylates.